Such phenotype has been demonstrated in colorectal cancer where high levels of lipid droplets (LD) correlate with CD133 antigen (also known as prominin-1) expression level and Wingless-type MMTV integration site family (Wnt)/β-catenin pathway activation [8], making LD abundance a marker of colorectal CSC. The gene discussed is PROM1; the disease is colorectal cancer.