The ranking of inhibition effects on brain glioma or glioma stem cells was as follows: multifunctional vinblastine liposomes > stearyl-R8 modified vinblastine liposomes ≥ TfR-T12 modified vinblastine liposomes > vinblastine liposomes > free vinblastine > multifunctional blank liposomes. The gene discussed is TFRC; the disease is central nervous system cancer.