The decrease in the prevalence of iron-deficient erythropoiesis after adjustment for malaria and AGP (IRC approach) resulted in a median decrease of 14.2 pps (range: 6.3–18.1 pps) compared with that of unadjusted iron-deficient erythropoiesis in PSC and a corresponding absolute median decrease of 9.5 pps (range: 6.4–14.2 pps) in WRA. The gene discussed is ATP5MK; the disease is malaria.