In PSC, depleted iron stores (ferritin concentration <12 μg/L) in the lowest-inflammation group was higher than in the highest-inflammation group, and, as expected, the reverse relation was shown for the prevalence of iron-deficient erythropoiesis (sTfR concentration >8.3 mg/L) and vitamin A deficiency (RBP concentration >0.70 μmol/L) in PSC. The gene discussed is TFRC; the disease is vitamin A deficiency.