To model polyglutamine disease, we used UAS-HTT16Q and UAS-HTT128Q for HD (Romero et al., 2008); and UAS-SCA327Q, UAS-SCA384Q (SCA3 is also known as ATX3; Warrick et al., 2005) and UAS-ATX182Q for ataxia (Fernandez-Funez et al., 2000). The gene discussed is ATXN3; the disease is cerebellar ataxia.