After adjusting for late stage and lymph node metastasis using multivariate Cox regression analysis, co-overexpression of Oct4, NEAT1 and MALAT1 in lung cancer patients showed a relative risk of death of 2.42 (P = 0.039; Table 2, right panel). The gene discussed is POU5F1; the disease is metastatic malignant neoplasm in the lymph nodes.