Similarly, knockdown of SNAI1 in RD cells using two different shRNAs resulted in significantly reduced tumor growth in vivo when assessed by luciferase imaging at 21 days and after tumors were palpable (Figures 6I–6K and S6F–S6J; p < 0.001, two-way ANOVA followed by Dunnett's multiple comparisons test). This evidence concerns the gene SNAI1 and neoplasm.