The observed resistance to the autologous CTL Heu171 clone attack can be partially explained by the absence of detectable E‐cadherin in the Mes IGR‐Heu cancer variants, as the cytolytic function of CTL Heu171 relies on integrin CD103 (αΕβ7 integrin), and its interactions with its preferred ligand, E‐cadherin (Franciszkiewicz et al., 2013; Le Floc'h et al., 2007). The gene discussed is CDH1; the disease is cancer.