IGHE and asthma: Allergic asthma accounts for about 80% of asthma cases, which is characterized by Th2 cytokines interleukin 4 (IL-4), IL-5 and IL-13 dependent increased immunoglobulin E (IgE) serum levels, lung eosinophilia, airway hyperresponsiveness and goblet cell metaplasia, respectively [17–19].