EGFR and oligodendroglioma: Moreover, genetic/epigenetic evidence is taken into account for the determination of prognosis and in the therapeutic decision-making, including signaling pathways and molecular markers such as mitotic marker MIB-1, isocitrate dehydrogenase 1 (IDH1) mutations, 1p/19q loss for oligodendrogliomas, epigenetic silencing of methylguaninmethyltransferase (MGMT) gene promoter, epidermal growth factor receptor (EGFR) amplification, and microRNAs [2, 4–9].