Overall survival results favored EP regardless of type of prior BM therapy [for surgery, patients randomized to EP had a median OS of 13.5 months compared to 3.2 months for TPC (HR 0.38); for radiotherapy, 10.0 and 5.1 months, respectively (HR 0.56)] or tumor subtype [HER2-positive, 16.1 vs. 8.6 months (HR 0.55); TNBC, 6.7 vs. 3.8 months (HR 0.27); and hormone receptor-positive, 12.2 vs. 5.2 months (HR 0.47)]. The gene discussed is ERBB2; the disease is neoplasm.