ELAVL1 and mesothelioma: Since the mutational reporter analysis had identified the ARE motif as a stabilizing element, we quantified the expression of HuR (stabilizer) along with TTP (destabilizer) across 10 mesothelioma cell lines and observed that HuR is abundantly expressed in all tested cells lines and 5- to 50-fold enriched compared to TTP (Figure 3B).