SERPINB3 and metabolic dysfunction-associated steatotic liver disease: To this aim we used two different experimental murine models: (i) chronic CCl4 administration, which results in post-necrotic bridging fibrosis resembling pan-lobular/parenchymal fibrosis found in the clinical conditions in which SerpinB3 expression has been best characterized2, 28, 29; (ii) mice fed with the MCD diet, that leads to pericellular/perisinusoidal fibrosis similar to that seen in human NAFLD/NASH2, 28, 29.