NRAP and hypertrophic cardiomyopathy: This observation is consistent with the study by Mohiddin et al. 5, who screened 50 patients with DCM or hypertrophic cardiomyopathy (HCM) which progressed to DCM for mutations in the NRAP gene and two members of a family with DCM linked to locus 10q24–26, and did not find any variants that could be classified as pathogenic.