Established sepsis biomarkers include cytokines (e.g. interleukin 6 and tumor necrosis factor alpha [TNF-α]), lactate, the acute-phase C-reactive protein, the pro-hormone procalcitonin and damage-associated molecular patterns (DAMPs)/cell surface receptors (e.g. triggering receptor expressed on myeloid cells-1) [2]. Here, TNF is linked to Sepsis.