Pretreatment of ILG significantly alleviated neurological deficits, cerebral infarct, and brain edema, and these neuroprotective effects are involved in the increases of brain ATP content, energy charge (EC) and total adenine nucleotides (TAN) and preservation of brain Na+ K+ ATPase activity, SOD, CAT, and GSH-Px, and inhibition of the increase of brain MDA content in a rat cerebral ischemia-reperfusion model [50]. Here, SOD1 is linked to brain infarction.