As the proteins HRNPM and SLC1A5 are related to the cell cycle regulators p21 or p27, the apoptosis regulators PTEN or PUMA, and the angiogenesis regulator VEGF-R2 it might be concluded, that both have a functional role in the pathogenesis of epithelial ovarian cancer. The gene discussed is PTEN; the disease is ovarian carcinoma.