Although no direct evidence shows miR‐29b‐3p could accelerate chondrocyte apoptosis at present, the inducing effect of miR‐29 family on apoptosis and cell cycle arrest has been described in a variety of tumour cell types and some normal cell types, including chronic myelogenous leukaemia cells 29, glioblastoma cells 30, neuronal cell 31 and multiple myeloma cells 32, and the mechanisms were usually associated with the regulation of BCR/ABL1, Mcl‐1, Bcl2. This evidence concerns the gene BCL2 and AL amyloidosis.