The association between HPA-2 polymorphism and CAD showed a significant difference utilizing the random-effects model in allele model (OR = 1.43, 95%CI = 1.07–1.91, P = 0.01) and dominant model (OR = 1.57, 95%CI = 1.08–2.28, P = 0.02) (Table 2). This evidence concerns the gene GP1BA and coronary artery disorder.