Secretion of Gal-3 induced by infection of gastric epithelial cells by H. pylori [31] occurs by a mechanism postulated to involve binding of the O-antigen side chain of H. pylori LPS to membrane Gal-3; coincidently, it was recently shown that extracellular recombinant Gal-3 is able to inhibit adhesion of H. pylori to the gastric epithelium [73]. Here, LGALS3 is linked to infection.