It was reported that rotenone—used in generating animal models of Parkinson's disease (PD)—increased CysLTR-1 expression in mouse microglial BV2 cell line [47, 48] and that treatment with the CysLTR-1 antagonist montelukast prevented phagocytosis and cytokine release [48]. This evidence concerns the gene CYSLTR1 and Parkinson disease.