Above all, the heterozygotes of GABRA5 SNP rs35586628 and GABRG3 SNP rs208129 showed the primary potential to increase the probability for ASD patients to undertake relevant core deficits, learning disabilities, and especially the decreased sensory sensitivity in voice and pain conformed abnormal sensory processing as one of the core features of individuals with ASD1. Here, GABRA5 is linked to atrial septal defect 1.