Nuclear FAM83H expression was significantly associated with high preoperative serum levels of α-fetoprotein (p = 0.026), higher tumor stage (p < 0.001), tumor size (p = 0.046), vascular invasion (p < 0.001), and cytoplasmic FAM83H expression (p < 0.001). The gene discussed is SACK1H; the disease is neoplasm.