In addition, when we evaluated the correlation of the immunohistochemical expression of FAM83H and MYC that have been reported previously in 152 HCC cases17, their expression patterns were significantly correlated with each other (Chi square test; p < 0.001 in between MYC and nuclear FAM83H expression, p = 0.017 in between FAM83H and cytoplasmic FAM83H expression). This evidence concerns the gene SACK1H and hepatocellular carcinoma.