After 15 days of treatment, CLD-rats treated with liraglutide displayed lower expression of α-SMA and PDGFRβ (Fig. 3A), accompanied by reductions in extracellular matrix synthesis and deposition as demonstrated by diminished collagen expression and hepatic fibrosis (Fig. 3B). Here, PDGFRB is linked to congenital secretory chloride diarrhea 1.