After 15 days of treatment, CLD-rats treated with liraglutide displayed lower expression of α-SMA and PDGFRβ (Fig. 3A), accompanied by reductions in extracellular matrix synthesis and deposition as demonstrated by diminished collagen expression and hepatic fibrosis (Fig. 3B). The gene discussed is ACTA1; the disease is congenital secretory chloride diarrhea 1.