Hypertrophic (HCM) and dilated (DCM) cardiomyopathies are heart muscle diseases caused by variants in genes encoding sarcomere proteins (Geisterfer-Lowrance et al., 1990; Seidman and Seidman, 1991; Konno et al., 2010), most commonly MYH7 (encoding cardiac β-myosin heavy chain; MHC) and MYPBC3 (encoding MyBP-C) and rarely in MYL2 and MYL3 that encode the ELC and RLC, respectively. This evidence concerns the gene MYH7 and familial dilated cardiomyopathy.