As shown in Table 1, we found that underexpression of miR-1296 was significantly associated with tumor-node-metastasis (TNM) stage (III + IV, P = 0.011), venous invasion (P = 0.024) and multiple tumor nodes (P = 0.012), while SRPK1 overexpression was correlated with venous invasion (P = 0.006) and advanced TNM stage (P = 0.001). This evidence concerns the gene SRPK1 and neoplasm.