ADH5 and cancer: None of the other potential targets (Glycosylphosphatidylinositol Anchored High Density Lipoprotein Binding Protein 1 (GPIHBP1), LIPA and Alcohol Dehydrogenase 5 (ADH5)) were essential in any of the tested cancer cell lines, but some of them were associated to various human diseases or have homozygous null mouse models with various phenotypes [71–73].