High levels of chemokines, such as CCL2/MCP-1, neutrophil chemoattractant, CX3CL1/fractalkine, CXCR2, CCR1, interleukin (IL)-6, IL-8, IL-10, and soluble TNF-gamma, have been reported in AP or CP [21–24]. Here, CXCR2 is linked to alkaline phosphatase measurement.