High levels of chemokines, such as CCL2/MCP-1, neutrophil chemoattractant, CX3CL1/fractalkine, CXCR2, CCR1, interleukin (IL)-6, IL-8, IL-10, and soluble TNF-gamma, have been reported in AP or CP [21–24]. This evidence concerns the gene CX3CL1 and alkaline phosphatase measurement.