CD44 and neoplasm: When comparing the expression of CD44 and CD66c at the same tumor stage, it was found that CD44 expression decreases in mtp53 versus wtp53 tumors in early stage tumors (p < 0.05) and that CD66c expression decreases in mtp53 versus wtp53 tumors in advanced stage of the disease (p < 0.05) (Figure 4A,B).