Colorectal cancer (CRC) stem cells express CD44, CD133, CD166, CD24, CD66c, CD29, the epithelial cell adhesion molecule, Musashi-1, aldehyde dehydrogenase-1 (ALDH1), and the leucine-rich-repeat containing G protein-coupled receptor 5 (LGR5) [5,6]. The gene discussed is CD44; the disease is colorectal carcinoma.