We found FoxP3 expression was strongly and positively correlated with Helios expression within TILs [Spearman’s rank correlation coefficient (rs) = 0.782, p = 0.01; Figure 3B] and in circulation in cancer patients (rs = 0.671, p = 0.02), suggesting that intratumoral and circulating Tregs have higher expression of FoxP3 with Helios. The gene discussed is FOXP3; the disease is cancer.