When patients were divided into four groups according to membranous PD‐L1 and HLA class I expression, negative membranous PD‐L1 expression and high HLA class I expression by PDA (n = 14) was associated with a significant better recurrence‐free survival (P < 0.001; Fig. S8A) and overall survival (p = 0.013; Fig. S8B) compared with patients HLA class I high and PD‐L1 positive (n = 4), HLA class I low and PD‐L1 negative (n = 16), or HLA class I low and PD‐L1 positive (n = 2) tumors. Here, CD274 is linked to Patent ductus arteriosus.