Moreover, transcript expression levels of GEP and GRP78 correlate significantly in HCC (Spearman’s ρ correlation coefficient = 0.382, P = 0.001), non-tumor (Spearman’s ρ correlation coefficient = 0.634, P < 0.001), and the tumor-to-non-tumor fold change (Spearman’s ρ correlation coefficient = 0.554, P < 0.001) (Fig. 4b-d). The gene discussed is HSPA5; the disease is hepatocellular carcinoma.