The AA genotype [odds ratio (OR) = 3.50, 95% confidence interval (CI) = 1.57–7.82, P = 0.0022], but not AG (OR = 1.28, 95% CI = 0.86–1.91, P = 0.2175), at IL-12A rs568408 demonstrated a statistically significant risk for asthma in Taiwan. The gene discussed is IL12A; the disease is asthma.