HOTAIR has been found to be deregulated in a variety of tumors, including lung23, colon12, stomach13, ovarian24, and esophageal cancers25 since it was first identified in breast cancer to promote tumor invasiveness and metastasis in 201010, HOTAIR is also found to be overexpressed in CC and predict a poor prognosis of patients14, 15. The gene discussed is HOTAIR; the disease is breast carcinoma.