With a median follow-up of 27.9 months, patients with high ANLN expression in tumor showed significantly poorer CSS (median, 22.4 vs. 37.3 months, p = 0.001), PFS (median, 19.7 vs. 27.9 months, p = 0.001) and RFS (median, 17.1 vs. 25.2 months, p = 0.011) compared with patients with low expression (Fig. 3E–G). Here, ANLN is linked to neoplasm.