Considering OX40 is found to be upregulated in MG, and our recently published data shows that soluble OX40L and Jagged-1 co-treatment can delay autoimmune diabetes in NOD mice while increasing Tregs, EAMG could be a successful candidate for OX40L and Jagged-1 co-treatment [157, 158, 207]. The gene discussed is JAG1; the disease is myasthenia gravis.