Adoptive transfer of FoxP3− Treg cells that ectopically expressed the transcription factor FoxA1 (suggested marker for a novel Treg) ameliorated EAE in IFN-β knockout (KO) mice and these cells were increased in response to treatment of MS patients with IFN-β, suggesting a role for this Treg subset [113]. Here, FOXP3 is linked to myeloid sarcoma.