To investigate if expression of ERα36 is altered in CML cells, we compared protein expression of ERα36 in IM-sensitive vs. IM-resistant K562 cells (K562IMR, a spontaneously derived cell line without BCR-ABL mutation) [43], BCR-ABL-transduced human UT7 cells vs. BCR-ABL-T315I mutant-transduced cells and BCR-ABL+ BV173 blast cells, using FACS analysis. Here, BCR is linked to chronic myelogenous leukemia, BCR-ABL1 positive.