Interestingly, CD34+ CML cells from subsequent IM-nonresponders (n = 5) displayed significantly high levels of ERα36 expression compared to CD34+ cells from IM-responders (n = 3) and NBM cells (n = 4, 2-3 fold, P < 0.01, Figure 1B). This evidence concerns the gene CD34 and chronic myelogenous leukemia, BCR-ABL1 positive.