The marker SNP rs10936602 maps to 3q26.2, a region amplified in 15% of ccRCC tumours in KIRC20; several notable nearby genes could represent possible candidate genes, including MECOM, a transcriptional regulator frequently amplified in RCC20, and TERC, encoding a component of telomerase, in which mutations cause autosomal dominant dyskeratosis congenita and aplastic anaemia33. Here, MECOM is linked to neoplasm.