In addition, upregulated expression of IFN-inducible chemokines cxcl9, cxcl10, cxcl11 and cxcl16 (ref. 26) was also seen in mouse and human tumours following radiation doses unable to induce Trex1 (Fig. 1d and Supplementary Figs 1e and 3a,b). The gene discussed is TREX1; the disease is neoplasm.