In addition, upregulated expression of IFN-inducible chemokines cxcl9, cxcl10, cxcl11 and cxcl16 (ref. 26) was also seen in mouse and human tumours following radiation doses unable to induce Trex1 (Fig. 1d and Supplementary Figs 1e and 3a,b). This evidence concerns the gene CXCL16 and neoplasm.