The most common AEs that led to discontinuation (≥1% of patients) were diabetes mellitus (3.7%), diarrhoea (3.7%), hyperglycaemia (3.7%), elevated gamma-glutamyltransferase (3.1%), elevated alanine aminotransferase (1.2%), cholelithiasis (1.2%), fatigue (1.2%), and nausea (1.2%). The gene discussed is GPT; the disease is cholelithiasis.