CD8A and Autoimmunity: However, in a model of autoimmunity, where TCR-transgenic CD8+ T cells from female mice specific for the male HY-antigen are transferred into male mice, IL-2, -12, and -15 were all dispensable for the formation of P-selectin ligands (67), arguing that antigen recognition may be sufficient to stimulate core 2 O-glycan synthesis in CD8+ T cells.