Finally, Ki67 and Tunel staining of the tumor sections showed that the miR-125a group contained fewer Ki67-positive and more Tunel-positive cells than those of the control, HK2, and miR-125a plus HK2 groups and the HK2 group had more Ki67-positive and less Tunel-positive cells than the control and miR-125a plus HK2 groups (Figs 6j and 5f and g). This evidence concerns the gene HK2 and neoplasm.