ANXA5 and systemic lupus erythematosus: SLE at the doses of 100, 200, 300 and 400 μg/mL significantly increased the rate of Annexin V positive cells to 14.2 ± 4.7%, 16.9 ± 4.0%, 20.4 ± 4.3% and 31.2 ± 4.0%, respectively, as compared with the untreated cells (5.7 ± 1.3%) (Fig. 3A and B).