RNASE1 and major depressive disorder: We recently reported elevated levels of cell death-inducing DFFA-like effector c (CIDEC), solute carrier family 36 member-1 (SLC36A1), ribonuclease 1 (RNASE1), and serine/threonine/tyrosine interacting-like 1 (STYXL1) in patients with late-onset MDD and in ovariectomized mice exposed to CUMS, which is an animal model of postmenopausal depression15.