Positive immunoreactivity to anti-CK antibodies AE1/AE3, as well as EMA (a marker for the epithelial nature of neoplastic cells), p63, and p40 (markers of squamous and basal cell carcinomas) are the usual immunohistochemical findings and should raise the suspicion of NUT carcinoma in young individuals with a midline tumor [6]. Here, MUC1 is linked to nut midline carcinoma.