Several peripheral blood leukocyte adhesion molecules have been reported as contributing to a connection between systemic inflammation and neuroinflammation in PD, including macrophage antigen complex-1 (Mac-1) [4], lymphocyte function-associated antigen 1 (LFA-1) [5], E-selectin [6], and P-selectin [7]. The gene discussed is SELP; the disease is Parkinson disease.