However, one mouse model overexpressing mutant Hsp27 has been shown to recapitulate many key symptoms of CMT/dHMN, exhibiting a late onset, mild neuropathy, manifesting in reduced motor and sensory nerve conduction velocity and reduced compound muscle action potential (CMAP) between 6 and 10 months of age (19,20). The gene discussed is HSPB1; the disease is neuropathy.