We first examined the effects of CMT-causing Hsp27 mutations on neuronal survival in the presence and absence of cell stressors in differentiated SH-SY5Y neuroblastoma cells resulted in 22–25% transfection efficiency (Supplementary Material, Fig. S1A), with no significant difference in the transfection efficiency of different genotypes (Supplementary Material, Fig. S1B). This evidence concerns the gene HSPB1 and neuroblastoma.