In TB+MSC- mice, lung CD4+ and effector CD4+CD62L- lymphocytes were significantly more activated and contained higher percent of CD69+ cells (2,5 fold, p<0,0001) and IFN-γ producing cells (27,3 fold, p<0,0001) compared to TB-MSC- mice (Fig 2C and 2F). The gene discussed is SELL; the disease is tuberculosis.