Zhuang and Deng et al. revealed that CCAT1 promotes the proliferation and migration of hepatocellular carcinoma cells and laryngeal squamous cell carcinoma cells by functioning as a molecular sponge for let-7 and enhanced the expression of HMGA2 and Myc, the direct target genes of let-7[8, 29]. Here, HMGA2 is linked to laryngeal squamous cell carcinoma.