Colon cancer–associated transcript-1 (CCAT1,CARLo-5) is a lncRNA with 2628 base pairs in length and CCAT1 gene is located on chromosome 8q24.21 and in the vicinity of c-MYC, a well-known transcription factor[12].CCAT1 is aberrantly expressed in a variety of human cancers, including colon cancer, non-small cell lung cancer, hepatocellular carcinoma and esophageal squamous cell carcinoma etc., and has been shown to promote tumor cell proliferation, invasion and metastasis through various mechanisms[8, 9, 13–15]. Here, MYC is linked to hepatocellular carcinoma.