Histopathological evaluation of lung fibrosis was further performed using an established Ashcroft scoring method.20 Fibrotic score was further decreased in the BLM+twice Apo+Simv group, compared to the BLM+Apo (single or twice) or the BLM+single Apo+Simv groups (Figure 8c). The gene discussed is AOPEP; the disease is pulmonary fibrosis.